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taj pharma api calcitonin

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HOME >> API >> API List1 >> Calcitonin >> Precautions

taj pharma api calcitonin CAS No. 47931-85-1

PRECAUTIONS
Calcitonin  CAS No. 47931-85-1

A large and diverse set of effects has been attributed to calcitonin, but in many cases, these were seen in response to pharmacologic doses of the hormone, and their physiologic relevance is suspect. It seems clear however, that calcitonin plays a role in calcium and phosphorus metabolism. In particular, calcitonin has the ability to decrease blood calcium levels at least in part by effects on two well-studied target organs:

* Bone: Calcitonin suppresses resorption of bone by inhibiting the activity of osteoclasts, a cell type that "digests" bone matrix, releasing calcium and phosphorus into blood.
* Kidney: Calcium and phosphorus are prevented from being lost in urine by reabsorption in the kidney tubules. Calcitonin inhibits tubular reabsorption of these two ions, leading to increased rates of their loss in urine.

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