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HOME >> API >> API List 2 >> Gabapentin >> Precautions

Gabapentin CAS number 60142-96-3

Gabapentin CAS number 60142-96-3

In children, gabapentin may cause behavioral and emotional disorders. The drug should be used cautiously and the dosage should be reduced in those with severe kidney disease. In experimental animals, gabapentin caused tumors to develop; however, it is not known if this occurs in humans.

Patients should take gabapentin only as prescribed. The drug should never be stopped abruptly because doing so increases the likelihood of having a seizure. Since gabapentin can cause dizziness and fatigue, patients should avoid driving or operating complex machinery until they know whether the drug adversely affects their reaction time or impairs their judgment.

Gabapentin should not be discontinued abruptly after long term use. Abrupt or over rapid withdrawal may provoke a withdrawal syndrome similar to alcohol or benzodiazepine withdrawal. Gradual reduction over a period of weeks or months helps minimise or prevents the withdrawal syndrome

Before taking gabapentin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease. This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages as they may worsen these effects. Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially swollen arms/legs or loss of coordination. Caution is advised when using this drug in children because they may be more sensitive to its effects, especially the mental/mood changes (e.g., hostility). This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. Gabapentin passes into breast milk. Because the effects of this drug on the nursing infant are unknown, consult your doctor before breast-feeding.

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