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Irbesartan Taj API

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HOME >> API >> API List 2 >> Irbesartan >> Drug Desciption

Irbesartan CAS number 138402-11-6

Irbesartan CAS number 138402-11-6

Irbesartan is a white to off-white crystalline powder with a molecular weight of 428.5. It is a nonpolar compound with a partition coefficient (octanol/water) of 10.1 at pH of 7.4. Irbesartan is slightly soluble in alcohol and methylene chloride and practically insoluble in water.

Irbesartan is among a class of drugs called angiotensin receptor blockers and is similar to losartan (Cozaar) and valsartan (Diovan). All three drugs block angiotensin II, a chemical that causes the arteries and veins to narrow, from attaching to the arteries and veins and causing them to narrow. As a result, the arteries and veins dilate (become larger), and blood pressure is reduced. When the blood pressure is reduced, the heart doesn't have to work as hard to pump blood.

This drug is used in adults and in children 6 years of age and older to treat high blood pressure (hypertension) and to help protect the kidneys from damage due to diabetes . This drug works by blocking the hormone angiotensin thereby relaxing blood vessels, causing them to widen. High blood pressure reduction helps prevent strokes, heart attacks, and kidney problems.

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