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HOME >> API >> API List 2 >> Mirtazapine >> Interaction

Mirtazapine CAS Number 61337-67-5

INTERACTION
Mirtazapine CAS Number 61337-67-5

Use of mirtazapine with antidepressants referred to as monoamine oxidase inhibitorssuch as tranylcypromineandphenelzine

is strongly prohibited due to the potential for high fever, muscle stiffness, sudden muscle spasms, rapid changes in heart rate and blood pressure, and the possibility of death. In fact, there should be a lapse of at least 14 days between taking an MAOI and mirtazapine.

Because mirtazapine may cause drowsiness, it should be used carefully with other medications that also make people prone to sleepiness, such as antidepressants, antipsychotics, antihistamines, anti-anxiety agents, and alcohol. Increased sleepiness has been reported when mirtazapine was used with both alcohol and the anti-anxiety drug diazepam.
 

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