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Molecular Weight 377.86






HOME >> API >> API List 2 >> Naltrexone Hcl >> Consumer Information

Naltrexone Hcl ,CAS Registry Number 16676-29-2

Naltrexone Hcl CAS Registry Number 16676-29-2

WARNING: Naltrexone can cause liver problems when given in large doses. Stop using this medication and tell your doctor immediately if symptoms of liver problems develop (e.g., persistent nausea, abdominal/stomach pain, yellowing eyes/skin, pale stools, dark urine).

This medication should not be used in patients who already have liver problems (e.g., active hepatitis, liver failure)

USES: This medication is used to prevent people who have been addicted to certain drugs (opiates) from taking them again. It is used as part of a complete treatment program for drug abuse (e.g., compliance monitoring, counseling, behavioral contract, lifestyle changes). This medication must not be used in people currently taking opiates, including methadone. Doing so can cause sudden withdrawal symptoms.

Naltrexone belongs to a class of drugs known as opiate antagonists. It works in the brain to prevent opiate effects (e.g., feelings of well-being, pain relief). It also decreases the desire to take opiates.

HOW TO USE: Take this medication by mouth with or without food, usually 50 milligrams once daily or as directed by your doctor. This medication may be given as part of a program where a health care professional will watch you take the medication. In this case, your doctor may order a higher dose (100-150 milligrams) to be taken every 2-3 days to make it easier to schedule clinic visits. Naltrexone may be taken with food or antacids if stomach upset occurs. A urine test should be done to check for recent opiate drug use. Your doctor may give you another medication (naloxone challenge test) to check for opiate use. Do not use any opiates for at least 7 days before starting naltrexone.

PRECAUTIONS:This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: taken any type of  drugs in the last 7 to 10 days, current  dependence, active liver disease/liver failure.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver problems.

MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. STORAGE: Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted.

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