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HOME >> API >> API List 4 >> Oxycodone >> Consumer Information

Oxycodone CAS number 76-42-6

CAS number 76-42-6

WARNING: This medication is a strong narcotic pain reliever similar to morphine. This medication is used to treat moderate to severe pain that is expected to last for a long period of time. It should be used on a regular schedule as prescribed by your doctor, not on an as-needed basis. You should use the 60 milligrams, 80 milligrams, or 160 milligrams tablets only if you have been taking moderate to large amounts of a potent narcotic medication (e.g., morphine). Use of these high-strength tablets by someone who is not regularly taking narcotic medications can cause serious (possibly fatal) breathing problems (e.g., very slow and shallow breathing).

USES: This drug is used to treat moderate to severe chronic pain (e.g., cancer pain). This medication acts on certain centers in the brain to give you pain relief. It is a long-acting narcotic pain reliever (opiate-type).

This medication should not be used as needed for mild pain which will go away in a few days or for prevention of pain after surgery. If you have not been on this medication before surgery, you should not use it for acute pain in the first 12 to 24 hours after surgery.

HOW TO USE:Take this medication by mouth, usually twice daily (every 12 hours) or as directed by your doctor. Do not crush, chew, or break the tablets. Take this drug either always with food, or always on an empty stomach (one hour before or two hours after a meal). If you have nausea, you may take this drug with food. If nausea persists or worsens, consult your doctor or pharmacist about alternatives for decreasing nausea (e.g., antihistamines, lying down for 1-2 hours with minimal head movement). If you have been using other long-acting narcotic pain medications or narcotic patches regularly, check with your doctor or pharmacist since they may need to be discontinued before starting this medication. If you are currently using a narcotic-containing patch (e.g., fentanyl), the effects may continue after removal of the patch. This medication may cause dependence, especially if it has been used regularly for an extended period of time (more than a few weeks), or if it has been used in high doses. If you suddenly stop this drug, withdrawal reactions (e.g., anxiety, irritability, sweating, trouble sleeping, diarrhea) may occur. Report any such reactions to your doctor immediately. When stopping extended regular use of this medication, gradually reducing the dosage as directed will help prevent withdrawal reactions. Consult your doctor or pharmacist for more details.

SIDE EFFECTS: Nausea, vomiting, constipation, mild itching, drowsiness, dry mouth, lightheadedness, loss of appetite, or weakness may occur. Some of these side effects may decrease after continued use of the medication. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

To prevent constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. Consult your pharmacist for help in the use of a laxative (e.g., stimulant-type and stool softener).

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other narcotic pain relievers (e.g., codeine, hydrocodone); or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: serious breathing problems (e.g., severe asthma, respiratory depression, hypercapnia), certain bowel diseases (e.g., paralytic ileus), intoxication with medications that depress the nervous system or your breathing (CNS/respiratory depressants such as alcohol or tranquilizers/sedatives).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: brain disorders (e.g., seizure, head injury, increased intracranial pressure), adrenal gland problem (e.g., Addison's disease), difficulty urinating (e.g., enlarged prostate, urethral stricture), personal or family history of regular use/abuse of drugs/alcohol/other substances, kidney or liver disease, heart problems (e.g., low blood pressure, irregular heartbeat), lung diseases (e.g., chronic obstructive pulmonary disease, hypoxia), metabolic disorders (e.g., low sodium, low body water), disease of the pancreas (pancreatitis), psychiatric problems (e.g., major depression, toxic psychosis), spinal problems (kyphoscoliosis), stomach/intestinal problems (e.g., gallbladder disease, severe diarrhea or constipation), underactive thyroid (hypothyroidism).

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature, 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59 and 86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets. Talk to your pharmacist about the proper disposal of this medication after you stop taking it.

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