CAS number 123-62-6
PROPIONIC ANHYDRIDE EINECS NO. 204-638-2
MOL WT. 130.14
H.S. CODE 2915.90
TOXICITY Oral rat LD50: 2360 mg/kg
SYNONYMS methylacetic anhydride; Propionyl oxide;
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE clear liquid
MELTING POINT -45 C
BOILING POINT 167 C
SPECIFIC GRAVITY 1.01
SOLUBILITY IN WATER Insoluble (decomposes slowly) pH
VAPOR DENSITY 4.5
AUTOIGNITION 285 C
NFPA RATINGS Health: 3 Flammability: 2 Reactivity: 1
REFRACTIVE INDEX 1.403 - 1.405
FLASH POINT 63 C
STABILITY Stable under ordinary conditions
Propionic anhydride is chiefly used as a raw material for
cellulose acetate propionate, a plaxtic found in face shields,
sunglasses, brush handles, toys, cosmetics containers and blister
packages. Propionic anhydride is also a raw material for dyes,
pharmaceuticals, agrochemicals and fragrance chemicals.
Appearance: colourless liquid with an unpleasant odour
Melting point: -45 C
Boiling point: 167 C
Vapour density: 4.5 (air = 1)
Density (g cm-3): 1.01
Flash point: 63 C
Explosion limits: 1.3 - 9.5%
Water solubility: decomposes
Stable. Combustible. Incompatible with strong oxidizing agents,
water, moisture, most common metals, active halogen compounds,
Safety glasses, good ventilation.
Air & Water Reactions
Decomposes exothermically in water to form a corrosive solution of
propionic acid [Merck, 11th ed. 1989].
Combustible material: may burn but does not ignite readily.
Substance will react with water (some violently) releasing
flammable, toxic or corrosive gases and runoff. When heated, vapors
may form explosive mixtures with air: indoors, outdoors and sewers
explosion hazards. Most vapors are heavier than air. They will
spread along ground and collect in low or confined areas (sewers,
basements, tanks). Vapors may travel to source of ignition and flash
back. Contact with metals may evolve flammable hydrogen gas.
Containers may explode when heated or if contaminated with water.
Inhalation causes irritation of eyes and respiratory tract. Contact
with liquid causes burns of eyes and skin. Ingestion causes burns of
mouth and stomach. (USCG, 1999)
PROPIONIC ANHYDRIDE reacts exothermically with water. The reactions
are sometimes slow, but can become violent when local heating
accelerates their rate. Acids accelerate the reaction with water.
Incompatible with acids, strong oxidizing agents, alcohols, amines,
Separated from acids, bases, oxidants, food and feedstuffs. Dry.
Ventilation along the floor.
DESCRIPTION AND APPLICATIONS
Propionic anhydride is a clear liquid with an unpleasant odour. It
hydrates with water producing corrosive propionic acid. It is
miscible in most organic solvents and decomposes with alcohol.
Propionic anhydride used as an intermediate to produce dyes,
pharmaceuticals, agrochemicals and other organic compounds.
CONTENT 98.0% min
PROPIONIC ACID 2.0% max
OTHER INDIVIDUAL IMPURITY 0.5% max
COLOR 20 max (Pt/Co scale)
Propanoic anhydride is strong smelling and corrosive, and will cause
burns on contact with skin. Vapour can burn eyes and lungs.
Notification: These chemicals are designated as those that are
used in the manufacture of the controlled substances and are
important to the manufacture of the substances. For any (Control
Substance) products Import and Export *** subjected to your
country government laws /control substance ACT.
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