Cas No 315-37-7
Endocrine and Urogenital, Female - The most common
side effects of androgen therapy are amenorrhea and other menstrual
irregularities, inhibition of gonadotropin secretion, and
virilization, including deepening of the voice and clitoral
enlargement. The latter usually is not reversible after androgens
are discontinued. When administered to a pregnant woman, androgens
cause virilization of the external genitalia of the female fetus.
Male - Gynecomastia, and excessive frequency and duration of penile
erections. Oligospermia may occur at high dosages.
Skin and Appendages - Hirsutism, male pattern
baldness, and acne.
Fluid and Electrolyte Disturbances - Retention of
sodium, chloride, water, potassium, calcium, and inorganic
Gastrointestinal - Nausea, cholestatic jaundice,
alterations in liver function tests; rarely, hepatocellular
neoplasms, peliosis hepatis.
Hematologic - Suppression of clotting factors II,
V, VII, and X; bleeding in patients on concomitant anticoagulant
Nervous System - Increased or decreased libido,
headache, anxiety, depression, and generalized paresthesia.
Metabolic - Increased serum cholesterol.
Miscellaneous - Rarely, anaphylactoid reactions;
inflammation and pain at injection site.