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HOME >> API >> API List1 >> Budesonide >> Drug Description

Budesonide CAS number 51333-22-3

DRUG DESCRIPTION
Budesonide CAS number 51333-22-3

Budesonide is a man-made glucocorticoid steroid related to the naturally-occurring hormone, cortisol or hydrocortisone which is produced in the adrenal glands. It is used for treating asthma by inhalation. Glucocorticoid steroids such as cortisol or budesonide have potent anti-inflammatory actions that reduces inflammation and hyper-reactivity (spasm) of the airways caused by asthma. When used as an inhaler, the budesonide goes directly to the inner lining of the inflamed airways to exert its effects. Only 39% of an inhaled dose of budesonide is absorbed into the body, and the absorbed budesonide contributes little to the effects on the airways

Budesonide is provided as the mixture of two epimers (22R and 22S).Budesonide is a white to off-white, odorless powder that is practically insoluble in water and in heptane, sparingly soluble in ethanol, and freely soluble in chloroform.Its partition coefficient between octanol and water at pH 5 is 1.6 x 10.3

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