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PRECAUTION
Duloxetine HCl
CAS number 136434-34-9
Before taking duloxetine, tell your doctor or pharmacist if you are
allergic to it; or if you have any other allergies.
This medication should not be used if you have certain medical conditions.
Before using this medicine, consult your doctor or pharmacist if you have:
severe kidney disease, liver disease.
Before using this medication, tell your doctor or pharmacist your medical
history, especially of: personal or family history of psychiatric disorders
(e.g., bipolar/manic-depressive disorder), personal or family history of
suicide attempts, diabetes, glaucoma (narrow-angle), kidney disease, stomach
problems (e.g., bleeding or slow emptying of the stomach), low sodium in the
blood, severe loss of body water (dehydration), drug or alcohol abuse,
seizure disorder.
This drug may make you dizzy or drowsy. Use caution while driving, using
machinery, or doing any other activity that requires alertness. Avoid
alcoholic beverages. Drinking alcohol can also increase your risk of liver
problems.
To reduce dizziness and lightheadedness, get up slowly when rising from a
sitting or lying position. Dizziness is more common when you start taking
this medication and when your dose is increased.
If you have diabetes, duloxetine may affect your blood sugar levels. Monitor
your blood sugar regularly and share the results with your doctor. Your
doctor may need to adjust your medication, diet, and exercise when you start
or stop duloxetine.
Caution is advised when using this product in the elderly because they may
be more sensitive to its effects. The elderly are more likely to lose too
much salt (hyponatremia), especially if they are also taking "water pills"
(diuretics) with this medication.
This medication is not recommended for use during pregnancy. It may harm an
unborn baby. Also, babies born to mothers who have used this drug during the
last 3 months of pregnancy may infrequently develop withdrawal symptoms such
as feeding/breathing difficulties, seizures, muscle stiffness, or constant
crying. If you notice any of these symptoms in your newborn, tell the doctor
promptly.
Since untreated depression can be a serious condition, do not stop taking
this medication unless directed by your doctor. If you are planning
pregnancy, become pregnant, or think you may be pregnant, immediately
discuss the benefits and risks of using this medication during pregnancy
with your doctor.
This drug may pass into breast milk and could have undesirable effects on a
nursing infant. Therefore, breast-feeding is not recommended while using
this drug. Consult your doctor before breast-feeding.
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