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Eszopiclone Taj Pharmaceuticals Ltd.

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Molecular Structure Eszopiclone,






 








 

 

HOME >> API >> API List1 >> Eszopiclone >> Pharmalogy

Eszopiclone CAS #: 138729-47-2

PHARMALOGY
Eszopiclone CAS NO: 138729-47-2

Eszopiclone acts on benzodiazepine receptors as an agonisEszopiclone is rapidly absorbed after oral administration, with serum levels peaking between 1 and 1.3 hoursThe elimination half-life of eszopiclone is approximately 6 hours and is extensively metabolized by oxidation and demethylation. Approximately 52% to 59% of a dose is weakly bound to plasma protein. Cytochrome P450 (CYP) isozymes CYP3A4 and CYP2E1 are involved in the biotransformation of eszopiclone; thus, drugs that induce or inhibit these CYP isozymes may affect the metabolism of eszopiclone. Less than 10% of the orally administered dose is excreted in the urine as racemic zopicloneIn terms of benzodiazepine receptor binding and relevant potency, 3 mg of eszopiclone is equivalent to 10 mg of diazepam

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