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taj pharma ltd. Fosphenytoin Sodium

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HOME >> API >> API List1 >> Fosphenytoin Sodium >> Dosage

Fosphenytoin Sodium CAS number 93390-81-9

DOSAGE
Fosphenytoin Sodium

The dose, concentration in dosing solutions, and infusion rate of IV is expressed as phenytoin sodium equivalents (PE) to avoid the need to perform molecular weight-based adjustments when converting between fosphenytoin and phenytoin sodium doses.should always be pre scribed and dispensed in phenytoin sodium equivalent units (PE).has important differences in administration from those for parenteral phenytoin sodiumThe loading doseis 15 to 20 mg PE/kg administered at 100 to 150 mg PE/min.

Because of the risk of hypotension, fosphenytoin should be administered no faster than 150 mg PE/min. Continuous monitoring of the electrocardiogram, blood pressure, and respiratory function is essential and the patient should be observed throughout the period where maximal serum phenytoin concentrations occur, approximately 10 to 20 minutes

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