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HOME >> API >> API List1 >> Fosphenytoin Sodium >> Interaction

Fosphenytoin Sodium CAS number 93390-81-9

INTERACTION
Fosphenytoin Sodium

Drug-drug. Amiodarone, benzodiazepines, chloramphenicol, cimetidine, disulfiram, estrogens, felbamate, fluconazole, fluoxetine, halothane, influenza vaccine, isoniazid, itraconazole, ketoconazole, methylphenidate, miconazole, omeprazole, phenothiazines, phenylbutazone, salicylates, sulfonamides, tolbutamide, trazodone: increased fosphenytoin blood level

Antidepressants, antihistamines, opioids, sedative-hypnotics: additive CNS depression

Barbiturates, carbamazepine, reserpine: decreased fosphenytoin blood level

Corticosteroids, cyclosporine, doxycycline, estrogens, felbamate, methadone, quinidine, rifampin: altered effects of these drugs

Dopamine: additive hypotension

Lidocaine, propranolol: additive cardiac depression

Streptozocin, theophylline: decreased efficacy of these drugs

Warfarin: initial increase in warfarin effects in patients stabilized on warfarin therapy, followed by decreased response to warfarin

Drug-diagnostic tests. Alkaline phosphatase, glucose, hepatic enzymes: increased levels

Dexamethasone, metyrapone: test interference

Glucose tolerance test: decreased tolerance

Potassium, thyroxine: decreased levels

Thyroid function tests: decreased values

Drug-behaviors. Acute alcohol ingestion: increased drug blood level, additive CNS depression

Chronic alcohol ingestion: decreased drug blood level

Information Associated with Product:
DRUG DESCRIPTION
DOSAGE
SIDE EFFECTS
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