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Olanzapine Molecular Formula C17H20N4S

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Olanzapine Molecular Weight 312.43







HOME >> API >> API List 3 >> Olanzapine >> Dosage

Olanzapine CAS Registry Number 132539-06-1

Olanzapine CAS Registry Number 132539-06-1

The usual oral dose for treating schizophrenia is 10 mg once daily. Therapy is initiated with 5-10 mg/day and the dose may be increased by 5 mg a day in weekly intervals. Doses greater than 10 mg daily have not been shown to be more effective than 10 mg daily. The safety and efficacy of doses greater than 20 mg daily have not been evaluated.

Treatment of bipolar disorder usually is initiated with oral doses of 10-15 mg once daily. The dose may be increased by 5 mg daily at 24 hour intervals. Doses greater than 20 mg daily have not been evaluated. In clinical trials, doses of 5-20 mg daily were effective.

The usual dose for treating agitation due to schizophrenia or bipolar disorder is 10 mg administered by intramuscular injection. Additional 10 mg doses may be administered, but the efficacy of total daily doses greater than 30 mg daily have not been adequately evaluated.

Olanzapine is eliminated from the body more quickly in young people than in older (over age 60) individuals, in men than in women, and in smokers faster than in non-smokers. Dosage adjustments may be needed based upon individual patient characteristics.

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