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Caffeine Synthesis and properties

caffeine CAS 58--8-2

Cas No. [58-08-2]


Anhydrous (dry) USP-grade caffeine

In 1819, the German chemist Friedrich Ferdinand Runge isolated relatively pure caffeine for the first time. According to Runge, he did this at the behest of Johann Wolfgang von Goethe. In 1827, Oudry isolated "theine" from tea, but it was later proved by Mulder and Jobat that theine was the same as caffeine. The structure of caffeine was elucidated near the end of the 19th century by Hermann Emil Fischer, who was also the first to achieve its total synthesis. This was part of the work for which Fischer was awarded the Nobel Prize in 1902. The nitrogen atoms are all essentially planar (in sp2 orbital hybridization), resulting in the caffeine molecule having aromatic character. Being readily available as a byproduct of decaffeination, caffeine is not usually synthesized. If desired, it may be synthesized from dimethylurea and malonic acid.

caffeine molucular structure

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    Occurrence    
    History    
    Synthesis and properties >>    
    Pharmacology    
    Metabolism and half-life    
    Mechanism of action    
    Effects when taken in moderation    
    Tolerance and withdrawal    
    Overuse    
    Caffeine intoxication    
    Anxiety and sleep disorders    
    Effects on memory and learning    
    Effects on the heart    
    Effects on children    
    Caffeine intake during pregnancy    
    Decaffeination    
     

caffeine
 

We all know that one of the most powerful chemical compounds found in both coffee and tea is caffeine. Has caffeine become an important part of your daily life? Did you know
Article : What Is Caffeine?

Caffeine is a drug that is naturally produced in the leaves and seeds of many plants. It's also produced artificially and added to certain foods. Caffeine is defined as a drug because it stimulates the central nervous system, causing increased alertness. Caffeine gives most people a temporary energy boost and elevates mood.
Caffeine is in tea, coffee, chocolate, many soft drinks, and pain relievers and other over-the-counter medications. In its natural form, caffeine tastes very bitter. But most caffeinated drinks have gone through enough processing to camouflage the bitter taste.
Teens usually get most of their caffeine from soft drinks and energy drinks. (In addition to caffeine, these also can have added sugar and artificial flavors.) Caffeine is not stored in the body, but you may feel its effects for up to 6 hours.
 


Caffeine Cas No. [58-08-2]

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