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Lamotrigine is a novel anticonvulsant drug which has multiple mechanisms of action.

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HOME >> API >> API List 2 >> Lamotrigine >> Precautions

Lamotrigine CAS Registry Number 84057-84-1

Lamotrigine CAS Registry Number 84057-84-1

Before taking lamotrigine,

* tell your doctor and pharmacist if you are allergic to lamotrigine, or any other medications. If you will be taking the chewable dispersible tablets, tell your doctor if you are allergic to sulfa medications or saccharin.

* tell your doctor if you are taking female hormonal medications such as hormonal contraceptives (birth control pills, patches, rings, injections, implants, or intrauterine devices), or hormone replacement therapy (HRT). Talk to your doctor before you start or stop taking any of these medications while you are taking lamotrigine. If you are taking a female hormonal medication, tell your doctor if you have any bleeding between expected menstrual periods.

* tell your doctor if you have or have ever had heart, kidney, or liver disease or a blood disorder.

* tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking lamotrigine, call your doctor.

* if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking lamotrigine.

* you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.

* remember that alcohol can add to the drowsiness caused by this medication.

* you should know that your mental health may change in unexpected ways, and you may become suicidal (thinking about harming or killing yourself or planning or trying to do so) while you are taking lamotrigine for the treatment of epilepsy, mental illness, or other conditions. A small number of adults and children 5 years of age and older who took antiepileptics such as lamotrigine during clinical studies were found to be twice as likely to become suicidal than people who did not take the medication. This increased risk of suicidal behavior was seen as early as one week after starting the medication. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: anxiety, agitation, hostility, mania (frenzied, abnormally excited mood), talking or thinking about wanting to hurt yourself or end your life, withdrawing from friends and family, new or worsening depression, preoccupation with death and dying, or giving away prized possessions. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.

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