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Loratadine CAS number 79794-75-5

Loratadine
CAS number 79794-75-5

Loratadine Formula C22H23ClN2O2

Systematic (IUPAC) name
Ethyl 4-(8-chloro-5,6-dihydro-11H-
benzo[5,6]cyclohepta[1,2-b]pyridin-
11-ylidine)-1-piperidinecarboxylate
Identifiers
CAS number 79794-75-5
ATC code R06AX13
PubChem 3957
DrugBank APRD00384
ChemSpider 3820

Chemical data

Formula C22H23ClN2O2
Mol. mass 382.88 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability N/A due to extensive first-pass metabolism
Metabolism hepatic
Half life 8 hours (metabolites 12-24 hours)
Excretion 40% as conjugated metabolites into urine
similar amount into the feces
Therapeutic considerations
Pregnancy cat.

B1(AU) B(US)
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