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SIDE EFFECTS
Loratadine CAS number 79794-75-5
Headache, fatigue, dry mouth, thirst, dry nose or hoarseness may occur.
These effects should lessen as your body adjusts to the medication. If any
of these effects persist or worsen, notify your doctor or pharmacist
promptly. Tell your doctor immediately if any of these unlikely but serious
side effects occur: nervousness, rapid or pounding heartbeat, unusual
weakness, stomach pain, dizziness, diarrhea, wheezing, increased physical
activity. Loratadine does not usually cause drowsiness when used at
recommended doses and under normal circumstances. However, be sure of the
drug's effects before engaging in activities that require alertness such as
driving or using machinery. A serious allergic reaction to this drug is
unlikely, but seek immediate medical attention if it occurs. Symptoms of a
serious allergic reaction include: rash, itching, swelling, severe
dizziness, trouble breathing. If you notice other effects not listed above,
contact your doctor or pharmacist.
Non-sedating antihistamine
As a non-sedating antihistamine, loratadine causes less sedation and
psychomotor impairment than the older antihistamines because it penetrates
the blood brain barrier only to a slight extent.
Although drowsiness is rare, patients should nevertheless be advised that it
can occur and may affect performance of skilled tasks (e.g. driving); excess
alcohol should be avoided.
Most common side-effects
Drowsiness, headache, psychomotor impairment, and antimuscarinic effects
such as urinary retention, dry mouth, blurred vision, and gastrointestinal
disturbances are the most common side effects.
Other rarer side-effects
Hypotension, extrapyramidal effects, dizziness, confusion, depression, sleep
disturbances, lower back pain, tremor, convulsions, palpitation,
arrhythmias, hypersensitivity reactions (including bronchospasm, angioedema,
and anaphylaxis, rashes, and photosensitivity reactions), blood disorders,
liver dysfunction, and angle-closure glaucoma are less common side effects.

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