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Lacidipine CAS No 103890-78-4
Lacidipine is the first of a class of antihypertensive agents called
angiotensin II (AG II) receptor antagonists. It is, along with its longer
acting active metabolite (E-3174), a specific and selective AT1 receptor
antagonist. Lacidipine blocks the vasoconstrictor and aldosterone-secreting
effects of angiotensin II by selectively blocking the binding of angiotensin
II to the AT1 receptor found in many tissues, (e.g., vascular smooth muscle,
adrenal gland).
This belongs to the group of medicines known as calcium channel blockers.
Lacidipine is used to treat hypertension (high blood pressure).
Lacidipine works by relaxing and opening up the blood vessels. This allows
blood to circulate more freely around the body, lowering blood pressure and
allowing the heart to work more efficiently.
Lacidipine is available in tablet form.

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