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Modafinil Taj PharmaCeuticals Ltd.

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Modafinil Taj API






HOME >> API >> API List 2 >> Modafinil >> Dosage

Modafinil CAS Registry Number 68693-11-8

Modafinil CAS Registry Number 68693-11-8

Modafinil usually is taken at a dose of 200 or 400 mg daily, although the 400 mg dose has not been shown to be more effective than the 200 mg dose. Modafinil can be taken with or without food.

The recommended dose of Modafinil  is 200 mg given once a day.

For patients with narcolepsy and OSAHS, Modafinil  should be taken as a single dose in the morning.

For patients with SWSD, Modafinil  should be taken approximately 1 hour prior to the start of their work shift.

Doses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg dose
Dosage adjustment should be considered for concomitant medications that are substrates for CYP3A4, such as triazolam and cyclosporineIn patients with severe hepatic impairment, the dose of Modafinil  should be reduced to one-half of that recommended for patients with normal hepatic functionIn elderly patients, elimination of Modafinil  and its metabolites may be reduced as a consequence of aging. Therefore, consideration should be given to the use of lower doses in this population

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