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Paroxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant.

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HOME >> Pharmaceuticals API List 2 >> Paroxetine >> Precautions

Paroxetine  CAS number 61869-08-7
Paroxetine CAS number 61869-08-7

Before taking paroxetine,

* tell your doctor and pharmacist if you are allergic to paroxetine or any other medications.
* tell your doctor if you are taking monoamine oxidase (MAO) inhibitors, including isocarboxazid , linezolid , phenelzine  selegiline  Emsam, , and tranylcypromine , if you have stopped taking them within the past 2 weeks, or if you are taking thioridazine or pimozide . Your doctor will probably tell you not to take paroxetine. If you stop taking paroxetine, you should wait at least 2 weeks before you start to take an MAO inhibitor.
* tell your doctor and pharmacist what other prescription and nonprescription medications and vitamins you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin ; antidepressants ('mood elevators') such as amitriptyline , amoxapine , clomipramine , desipramine , doxepin , imipramine , nortriptyline , protriptyline , and trimipramine ; antihistamines; aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen , and naproxen ; atomoxetine ; atazanavir ; bromocriptine ; bupropion ; buspirone ; celecoxib ; chlorpromazine ; cimetidine ; clopidogrel ; codeine (found in many cough and pain medications); dexamethasone  dextromethorphan (found in many cough medications); diazepam ; dicloxacillin ; digoxin ; dipyridamole ; diuretics ('water pills'); haloperidol ; isoniazid ; lithium ; medications for irregular heartbeat such as amiodarone , encainide  flecainide , mexiletine , moricizine , propafenone , and quinidine ; medications for mental illness and nausea; medications for migraine headaches such as almotriptan , eletriptan , frovatriptan , naratriptan , rizatriptan , sumatriptan , and zolmitriptan ;medications for seizures such as phenobarbital and phenytoin ; meperidine ; methadone ; metoclopramide ; metoprolol ; ondansetron ; other selective serotonin reuptake inhibitors such as citalopram , fluoxetine , fluvoxamine , and sertraline ; procyclidine ; propoxyphene ; propranolol ; ranitidine ; rifampin ; risperidone; ritonavir ; sibutramine ; tamoxifen  terbinafine ; theophylline ; ticlopidine ; timolol ; tramadol ; trazodone ; and venlafaxine . Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
* tell your doctor if you use or have ever used street drugs or have overused prescription medications, if you have recently had a heart attack, and if you have or have ever had glaucoma (an eye disease); seizures; bleeding from your stomach or esophagus (tube that connects the mouth and stomach) or liver, kidney, or heart disease.
* tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking paroxetine, call your doctor.
* you should know that paroxetine may make you drowsy and affect your judgment and thinking. Do not drive a car or operate machinery until you know how this medication affects you.
* ask your doctor about the safe use of alcoholic beverages while you are taking paroxetine.

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