Pharmaceuticals API List 2 >>
Naratriptan >> Consumer Information
Naratriptan CAS number 121679-13-8
This medication is used to treat migraines. It helps to relieve headaches,
pain and other symptoms of migraines, including sensitivity to light/sound,
nausea, and vomiting. Prompt treatment allows you to get back to your normal
routine and may decrease your need for other pain medications. Naratriptan
does not prevent future migraines or reduce how often you may get a
Naratriptan belongs to a group of drugs called triptans. It affects a
certain natural chemical (serotonin) that constricts blood vessels in the
brain. It may also block other pain pathways in the brain.
How to use
Take one tablet by mouth with or without food, at the first sign of a
migraine, or as directed by your doctor. Do not take naratriptan to prevent
a migraine. If there is no improvement in your symptoms, do not take any
more doses of this medication before talking to your doctor. If your
symptoms are only partly relieved, or if your headache comes back, you may
take a second dose after 4 hours or as directed by your doctor. Do not take
more than 5 milligrams in a 24-hour period.
If you have never taken this medication before and you have risk factors for
heart disease (see Precautions), you may be advised to take your first dose
in your doctor's office in order to monitor for rare but serious heart
problems (e.g., heart attack).
This medication may rarely cause a very serious condition called serotonin
syndrome. The risk increases when this medication is taken with certain
other drugs such as other "triptans" used to treat migraine headaches (e.g.,
sumatriptan, zolmitriptan), certain antidepressants including SSRIs (e.g.,
citalopram, fluoxetine, paroxetine) and NSRIs (e.g., duloxetine, venlafaxine),
or a certain drug to treat obesity (sibutramine). Before taking this drug,
tell your doctor if you take any of these medications. Serotonin syndrome
may be more likely when you start or increase the dose of any of these
medications. Seek immediate medical attention if you develop some of the
following symptoms: hallucinations, unusual restlessness, loss of
coordination, fast heartbeat, severe dizziness, high fever, severe
nausea/vomiting/diarrhea, twitchy muscles.
This medication should not be taken if you have certain medical conditions.
Before using this medication, consult your doctor or pharmacist if you have
a history of: heart disease (e.g., chest pain, heart attack), decreased
blood flow in the brain (e.g., stroke, transient ischemic attack), blood
circulation disease (e.g., ischemic bowel disease), uncontrolled high blood
pressure (hypertension), certain types of headaches (hemiplegic or basilar
migraine), kidney disease, liver disease.
Before using this medication, tell your doctor or pharmacist your medical
history, especially of: certain blood circulation disorders (e.g., Raynaud's
Tell your doctor if you have the following risk factors for heart disease:
diabetes, family history of heart disease, high blood pressure (controlled),
high cholesterol, overweight, smoker, female after menopause, male over age
If you are at high risk for heart disease, your doctor may want to check
your heart before prescribing naratriptan.
This drug may make you dizzy or drowsy; use caution engaging in activities
requiring alertness such as driving or using machinery. Limit alcoholic
The risk of heart disease, liver disease, and high blood pressure increases
with age. The manufacturer does not recommend the use of naratriptan in the
elderly since they may be more sensitive to the side effects, especially to
an increase in blood pressure.
Store the US product at room temperature between 68 and 77 degrees F (20-25
degrees C) away from light and moisture.
Store the Canadian product below 86 degrees F (30 degrees C) away from light
Do not store in the bathroom. Keep all medicines away from children and